Pethig: Introductory Bioelectronics: For Engineers & Physical Scientists

Bioelectronics is a rich field of research involving the application of electronics engineering principles to biology, medicine, and the health sciences. With its interdisciplinary nature, bioelectronics spans state-of-the-art research at the interface between the life sciences, engineering and physical sciences.

Introductory Bioelectronics offers a concise overview of the field and teaches the fundamentals of biochemical, biophysical, electrical, and physiological concepts relevant to bioelectronics. It is the first book to bring together these various topics, and to explain the basic theory and practical applications at an introductory level.

The authors describe and contextualise the science by examining recent research and commercial applications. They also cover the design methods and forms of instrumentation that are required in the application of bioelectronics technology.

Supplying the tools to succeed, this text is the best resource for engineering and physical sciences students in bioelectronics, biomedical engineering and micro/nano-engineering. Not only that, it is also a resource for researchers without formal training in biology, who are entering PhD programmes or working on industrial projects in these areas.

Key Features

• An interdisciplinary approach, which develops theory through practical examples and clinical applications, and delivers the necessary biological knowledge from an electronic engineer’s perspective.
• A problem section in each chapter that readers can use for self-assessment, with model answers given at the end of the book along with references to key scientific publications.
• Discussions of new developments in the bioelectronics and biosensors fields, such as microfluidic devices and nanotechnology.

Contents

1 Basic Chemical and Biochemical Concepts

• 1.1 Chapter Overview
• 1.2 Energy and Chemical Reactions
• 1.3 Water and Hydrogen Bonds
• 1.4 Acids, Bases and pH
• 1.5 Summary of Key Concepts

2 Cells and their Basic Building Blocks

• 2.1 Chapter Overview
• 2.2 Lipids and Biomembranes
• 2.3 Carbohydrates and Sugars
• 2.4 Amino Acids, Polypeptides and Proteins
• 2.5 Nucleotides, Nucleic Acids, DNA, RNA and Genes
• 2.6 Cells and Pathogenic Bioparticles
• 2.7 Summary of Key Concepts

3 Basic Biophysical Concepts and Methods

• 3.1 Chapter Overview
• 3.2 Electrostatic Interactions
• 3.3 Hydrophobic and Hydration Forces
• 3.4 Osmolarity, Tonicity and Osmotic Pressure
• 3.5 Transport of Ions and Molecules across Cell Membranes
• 3.6 Electrochemical Gradients and Ion Distributions Across Membranes
• 3.7 Osmotic Properties of Cells
• 3.8 Probing the Electrical Properties of Cells
• 3.9 Membrane Equilibrium Potentials
• 3.10 Nernst Potential and Nernst Equation
• 3.11 The Equilibrium (Resting) Membrane Potential
• 3.12 Membrane Action Potential
• 3.13 Channel Conductance
• 3.14 The Voltage Clamp
• 3.15 Patch-Clamp Recording
• 3.16 Electrokinetic Effects

4 Spectroscopic Techniques

• 4.1 Chapter Overview
• 4.2 Introduction
• 4.3 Classes of Spectroscopy
• 4.4 The Beer-Lambert Law
• 4.5 Impedance Spectroscopy

5 Electrochemical Principles and Electrode Reactions

• 5.1 Chapter Overview
• 5.2 Introduction
• 5.3 Electrochemical Cells and Electrode Reactions
• 5.4 Electrical Control of Electron Transfer Reactions
• 5.5 Reference Electrodes
• 5.6 Electrochemical Impedance Spectroscopy (EIS)

6 Biosensors

• 6.1 Chapter Overview
• 6.2 Introduction
• 6.3 Immobilisation of the Biosensing Agent
• 6.4 Biosensor Parameters
• 6.5 Amperometric Biosensors
• 6.6 Potentiometric Biosensors
• 6.7 Conductometric and Impedimetric Biosensors
• 6.8 Sensors Based on Antibody–Antigen Interaction
• 6.9 Photometric Biosensors
• 6.10 Biomimetic Sensors
• 6.11 Glucose Sensors
• 6.12 Biocompatibility of Implantable Sensors

7 Basic Sensor Instrumentation and Electrochemical Sensor Interfaces

• 7.1 Chapter Overview
• 7.2 Transducer Basics
• 7.3 Sensor Amplification
• 7.4 The Operational Amplifier
• 7.5 Limitations of Operational Amplifiers
• 7.6 Instrumentation for Electrochemical Sensors
• 7.7 Impedance Based Biosensors
• 7.8 FET Based Biosensors

8 Instrumentation for Other Sensor Technologies

• 8.1 Chapter Overview
• 8.2 Temperature Sensors and Instrumentation
• 8.3 Mechanical Sensor Interfaces
• 8.4 Optical Biosensor Technology
• 8.5 Transducer Technology for Neuroscience and Medicine

9 Microfluidics: Basic Physics and Concepts

• 9.1 Chapter Overview
• 9.2 Liquids and Gases
• 9.3 Fluids Treated as a Continuum
• 9.4 Basic Fluidics
• 9.5 Fluid Dynamics
• 9.6 Navier-Stokes Equations
• 9.7 Continuum versus Molecular Model
• 9.8 Diffusion
• 9.9 Surface Tension

10 Microfluidics: Dimensional Analysis and Scaling

• 10.1 Chapter Overview
• 10.2 Dimensional Analysis
• 10.3 Dimensionless Parameters
• 10.4 Applying Nondimensional Parameters to Practical Flow Problems
• 10.5 Characteristic Time Scales
• 10.6 Applying Micro- and Nano-Physics to the Design of Microdevices 4

Appendices

• Appendix A: SI Prefixes
• Appendix B: Values of Fundamental Physical Constants
• Appendix C: Model Answers for Self-study Problems
• Index

About the Authors

• Professor Ronald Pethig, Bioelectronics, School of Engineering, University of Edinburgh He has PhD degrees in electrical engineering and physical chemistry, and a D.Sc degree for work in the field of biomolecular electronics. He is author of one book (Dielectric and Electronic Properties of Biological Materials, Wiley) and more than 200 scientific papers in the field of biomolecular electronics and dielectrophoresis. He has received several awards, including in 2001 being the first recipient of the Herman P Schwan Award for work in biodielectrics. He serves on the editorial boards of several scientific journals, including acting as editor-in-chief of the IET journal Nanobiotechnology.
• Stewart Smith, RCUK Academic Fellow, School of Engineering, University of Edinburgh He has a PhD in microelectronics and has authored over 60 scientific papers on subjects ranging from implantable drug delivery systems to test structures for the characterisation of MEMS processes. He is based at the Scottish Microelectronics Centre in Edinburgh where he works on the development of biomedical microsystems. He is a member of the technical committee for the IEEE International Conference on Microelectronic Test Structures.

Book Details

• Hardcover: 462 pages
• Publisher: Wiley; 1 edition (© 2012)
• Language: English
• ISBN-10: 1119970873
• ISBN-13: 978-1119970873
• Product Dimensions: 6.7 x 1 x 10 inches
• List Price: $80.00

Kalia: Biopolymers: Biomedical & Environmental Applications

Part I. Polysaccharides.

• 1. Hyaluronic Acid: A Natural Biopolymer.
• 2. Polysaccharide Graft Copolymers Synthesis, Properties and Applications.
• 3. Natural Polysaccharides: From Membranes to Active Food Packaging.
• 4. Starch as Source of Polymeric Materials.
• 5. Grafted Polysaccharides: Smart Materials of Future, Synthesis and Applications.
• 6. Chitosan: The Marine based Biopolymer for Applications.

Part II. Bioplastics and Biocomposites.

• 7. Biopolymers Based-on Carboxylic Acids Derived from Renewable Resources.
• 8. Characteristics and Applications of PLA.
• 9. Biobased Composites & Applications.

Part III. Miscellaneous Biopolymers.

• 10. Cassia Seed Gums: A Renewable Reservoir for Synthesizing High Performance Materials for Water Remediation.
• 11. Bacterial Polymers: Resources, Synthesis and Applications.
• 12. Gum Arabica: A Natural Biopolymer.
• 13. Gluten: A Natural Biopolymer.
• 14. Natural Rubber: Production, Properties, and Applications.
• 15. Electronic Structures and Conduction Properties of Biopolymers.

Part IV. Biopolymers for Specific Applications.

• 16. Applications of Biopolymers in Agriculture with Special Reference to Role of Plant Derived Biopolymers in Crop Protection.
• 17. Modified Cellulose Fibers as a Biosorbent for the Organic Pollutants.
• 18. Polymers and Biopolymers in Pharmaceutical Technology.
• 19. Biopolymers Employed in Drug Delivery.
• 20. Natural Polymeric Vectors in Gene Therapy.

Biopolymers: Biomedical & Environmental Applications is the most comprehensive and up-to-date volume covering biopolymers and their biomedical and environmental applications. This book focuses on biopolymers for both environmental and biomedical applications. It shows recent advances in technology in all areas from chemical synthesis or biosynthesis to end use applications. These areas have not been covered in a single book before and they include biopolymers for chemical and biotechnological modifications, material structures, characterization, processing, properties, and applications.

After the introduction which summarizes the importance of biopolymer in the market, the book covers almost all the topics related to polysaccharides, biofibers, bioplastics, biocomposites, natural rubber, gums, bacterial and blood compatible polymers, and applications of biopolymers in various fields.

The book is divided into four parts:

• Part 1 is devoted to natural polysaccharides. These are renewable, nontoxic and biodegradable and are on a par with and sometimes superior to synthetic materials.
• Part 2 covers bioplastics and biocomposites which will help in solving the environmental problems connected with petroleum-based plastic waste and its disposal.
• Part 3 covers different biopolymers such as gums, proteins, natural rubber and bacterial polymers and some of their applications.
• Part 4 includes applications of various biopolymers such as seed coating to protect against biotic stress, biosorbent for the organic pollutant, pharmaceutical technology, drug delivery, and gene therapy.

The volume will prove to be a very useful tool for scientists, academics, research scholars, polymer engineers and those in the pharmaceutical, biotechnology, environmental, medical, packaging, and chemical engineering industries.

About the Authors

• Susheel Kalia is Assistant Professor in the Department of Chemistry, Bahra University (Shimla Hills), India. He received his PhD from Punjab Technical University Jalandhar, India. He has 33 research papers to his credit in international journals along with 45 publications in proceedings of national & international conferences as well as several book chapters. He is a life member of the Asian Polymer Association and Indian Cryogenics Council. He has edited the book, Cellulose Fibers, Bio- and Nano- Polymer Composites (Springer 2011). He is currently working in the field of polymer composites, cellulose nanofibers, hydrogels and cryogenics.
• Luc Avérous is Director of the Laboratory of Engineering Polymers for Advanced Technologies at the University of Strasbourg, France. He obtained his PhD in science and polymer engineering from the School of Mines of Paris in 1995. For the last 15 years his major research projects have dealt with multiphase systems (blends, multilayers, biocomposites and nano-biocomposites) based on agro-resources (starch, lignins, chitosan, cellulose etc.) and biopolyesters (PLA, PHA, PCL etc.). He has been particularly involved in the study of the materials-process-properties chain. He has published more than 60 journal articles, 15 book chapters, has 2 patents to his name, and has co-edited 3 books. With his expertise in starch-based materials, and more generally in biopolymers, he is regularly invited to organise symposia and conferences.

Book Details

• Hardcover: 642 pages
• Publisher: Wiley-Scrivener; 1 edition (2011)
• Language: English
• ISBN-10: 0470639237
• ISBN-13: 978-0470639238
• Product Dimensions: 7.2 x 1.6 x 9.9 inches

List Price: $195.00